TO OUR EU CLIENTS:
Dear Clients, if you are ordering from inside the EU, please order through our Irish site https://www.franklpharma.ie/ to avoid post-Brexit VAT charges. If you are based in the UK, please order as usual through this site. And please accept our apologies for any delays.Results of the first UK trial conducted by Professor Anthony Chu and Dr Benedetta Brazzini (Ealing Hospital and The Marylebone Clinic)
The efficacy trial was conducted between September 1016 and September 2017. Patients were assessed during three visits over an eight week period at Ealing Hospital, west London, and the Marylebone Clinic, Harley Street, using the Psoriasis Area and Severity Index (PASI) and the Dermatology Life Quality Index DLQI).
The more widespread and severe a person’s symptoms, the higher their PASI score will be. The DLQI assesses the impact of a dermatological condition on a person’s well-being, where 30 indicates a high impact and a low level of well-being, and zero represents no impact and a high state of well-being.
There were 20 patients, 14 male, six female. Ages ranged from 11 to 79, with an average of 43.5.
PASI
Improvement of 0-25%: 3 patients (15%)
Improvement of 26-50%: 5 patients (25%)
Improvement of 51-75%: 8 patients (40%)
Improvement of 76-100%: 4 patients (20%)
DLQI
Improvement of 0-25%: 4 patients (20%)
Improvement of 26-50%: 3 patients (15%)
Improvement of 51-75%: 4 patients (20%)
Improvement of 76-100%: 9 patients (45%)
T 0 |
T 1-4 weeks |
T 2-8 weeks |
Patient |
comments |
PASI 11.1 DLQI 11 |
5.2 1 |
4 1 |
S1 |
|
PASI 18.9 DLQI 11 |
14 9 |
10.5 4 |
S2 |
|
PASI 10 DLQI 11 |
10 11 |
10 11 |
S3 |
No improvement had to start biologics |
PASI 5.2 DLQI 14 |
5.2 15 |
3.6 12 |
S4 |
|
PASI 3.6 DLQI 8 |
2 6 |
1.4 2 |
S5 |
|
PASI 6 DLQI 11 |
5 8 |
2 1 |
S6 |
|
PASI 6 DLQI 8 |
5 6 |
3 3 |
S7 |
|
PASI 11.1 DLQI 11 |
3.6 1 |
1 0 |
S8 |
|
PASI 3 DLQI 6 |
1.4 6 |
0 0 |
S9 |
|
PASI 5.2 DLQI 8 |
3.5 6 |
2 1 |
S10 |
|
PASI 7.8 DLQI 20 |
4.7 9 |
1 0 |
S11 |
|
PASI 13 DLQI 8 |
Dropped out because of no improvement |
|
S12 |
Had to start systemics MTX |
PASI 13.6 DLQI 17 |
10 13 |
2 1 |
S13 |
|
PASI 2.1 DLQI 7 |
1 1
|
1 1 |
S14 |
|
PASI 13.8 DLQI 18 |
11.5 15 |
8 10 |
S15 |
|
PASI 4.6 DLQI 16 |
3 10 |
2 8 |
S16 |
|
PASI 3.8 DLQI 16 |
6 5 |
2.8 7 |
S17 |
|
PASI 5.2 DLQI 4 |
4.8 4 |
4 3 |
S18 |
|
PASI 3 DLQI 2 |
2 1 |
1.2 1 |
S19 |
|
PASI 19.5 DLQI 18 |
8.7 8 |
4.9 * 3* |
S20 |
*Patient’s final readings were delayed by a week because of unconnected illness |